German physician and hygenist Gustav Jager, was the first to come up with the concept of human pheromones. He identified them as lipophilic compounds that are associated with skin and follicles that determine the individual signature of human odors.
There had been much research on pheromones but the best known one was done by Martha McClintock in 1971. She published a study showing that the menstrual periods of women who lived together tended to converge on the same time every month, an effect thought to be mediated by pheromones.
When McClintock first began studying menstrual synchrony in the 1970s, data addressing how one woman could affect the hormonal cycle of another was nonexistent. There were hints that the pheromones in question were associated with underarm secretions, but it took until 1998 for McClintock to show that fluids collected from a donor woman’s underarms, when applied to the upper lip of a female recipient, could hasten or delay the recipient’s menstrual period. The study was unable to identify the exact chemicals responsible but implies the possiblity of pheromones in humans.
There has been much debate over whether pheromones affect human behavior, however some reaserch has been able to point to some of the effects pheromones have on human beings. In 1999, Noam Sobel, PhD, and his colleagues at Stanford University used functional magnetic resonance imaging to show that the human brain responded to androstadienone even when subjects were unable to smell it. This was later confirmed in another study. In another study in 2001, Ivanka Savic, PhD, and her colleagues at the Karolinska Institute in Sweden reported that androstadienone and estratetraenol affected men and women’s brains differently. Androstadienone boosted hypothalamic activity only in women, while estratetraenol increased hypothalamic activity only in men. However, it is still unclear how the presence of pheromones is communicated to the brain.
Benson, Etienne. "Pheromones, in Context." American Psychological Association (APA). Web. 06 May 2011. <http://www.apa.org/monitor/oct02/pheromones.aspx>.